Culture collection and characterization

We, LB Bulgaricum, have a true variety of bacteria. The company owns a unique collection of lactic acid bacteria, which was maintained, developed and enriched in the laboratory “Culture Collection and characterization”. Currently, the laboratory has more than 1000 strains of lactic acid microorganisms, part of which is included in the content of our Bulgarian starter cultures for the production of original Bulgarian yogurt, a traditional dairy product, as well as in our specialized healthy probiotic product line, called Proway.
In recent years, our collection of lactic acid bacteria has been enriched not only from isolated bacteria from real nature and traditional dairy products, but also from human isolates.
Thanks to the great efforts of our experts, every year we have found and characterized different types of strains, such as Lactobacillus helveticus, Lactobacillus casei, Lactobacillus lactis, Bifidobacterium, etc. In addition to conducting technology stability and shelf-life testing, our colleagues are conducting studies to analyze the probiotic benefits of the new strains using various in vivo and in vitro methods. A portion of the new strains have the demonstrated ability to persist in the human gut, they also have strong adhesion ability and good immunostimulatory functions, as well as appropriate inhibitory ability for blood pressure, holesterol, etc. Using a phenotype microarray system, we obtain the most suitable conditions for the manifestation of the sought probiotic property. The laboratory studies the effect of consumption of products prepared with selected strains and starter cultures for Bulgarian yogurt on the fecal microflora and metabolites of volunteers by conducting clinical trials in collaboration with various hospitals.